Healthy Living

Monday, November 30, 2009

Not faking it: Startling research may prove prejudice wrong about chronic fatigue syndrome

Years ago, shortly after I fell in love with the book Seabiscuit and the then the movie that followed, I saw a news piece about the author Laura Hillenbrand. In her mid-30s at the time, Hillenbrand had been suffering from chronic fatigue syndrome (CFS) for twenty years.

She said that the four years it took her to write the account of the legendary race horse helped her to transcend her debilitating illness. She said, “Here was a story I could get lost in, with fascinating
subjects whose lives were complicated and vigorous — everything my life wasn’t. Writing it
helped me redefine myself, to become Laura the author instead of Laura the sick person. That was very rewarding.”

She was heaped with the kind of acclaim writers dream of having in their career. But the book that brought her all of that attention also inflamed the symptoms of CFS, including vertigo that she could only deal with by writing in long-hand with her eyes closed. The day after she turned in her manuscript, Hillenbrand said, her health collapsed.

I recall the intense sadness of Hillenbrand's story, and of her decades-long struggle to have the energy to get up and have breakfast, let alone find enough to write that kind of book. But the bigger picture of CFS and how its sufferers have been judged, mistreated, and misdiagnosed was just as haunting.

I thought of Hillenbrand immediately when I read the news last week that a breakthrough had been made -- the recognition that CFS is spread by a virus and is not a psychological affliction, a reaction to past abuse, or simply made up as it had so often been assumed.

The report takes some untangling to understand, but is worthwhile in getting because of what it may show about how prevalent and valid CFS really is.

The journal Science published a study revealing that a virus had been discovered in prostate tumors. The xenotropic murine leukemia virus-related virus, or XMRV, is believed to be the third in a line of human gammaretroviruses. It falls after H.I.V. and a type of viruses that cause lymphoma and leukemia. These viruses cause permanent infections that can be passed between humans.

The study also showed that XMRV to be overwhelmingly present in people suffering from chronic fatigue syndrome. Of the 101 participants studied, 67% had the virus.

Of the healthy participants in the control group of this study, 3.7% were found to have "active infections" from this virus. Although this number may seem slight, if it is projected to the larger American population, that would mean 10 million people in this country have the virus present in their cells.

It is noted that not everyone who carries XMRV will develop chronic fatigue syndrome. However, the estimation of how many Americans have it is startling - 1 million people, very close to the number of people who have H.I.V.

These viruses now seem to be scientifically linked, but there are vast differences in how they are treated and perceived, and what the outcome has been historically for sufferers.

One doctor specializing in the treatment of both AIDS and CFS, encapsulated those differences in this quote:

"My H.I.V. patients for the most part are hale and hearty,” she said, noting that billions of dollars have been spent on AIDS research. Many of my C.F.S. patients, on the other hand, are terribly ill and unable to work or participate in the care of their families," noted Dr. Nancy Klimas.

As an immunologist at the University of Miami School of Medicine, Dr. Klimas that she would rather have AIDS if given the choice, in part because of the billions of dollars of funding for its research.

This study could very well change how CFS is researched, medicated, and possibly, even prevented. The hope here is that millions of people who may develop the syndrome won't have to endure the physical and emotional pain that sufferers have for the 25 years CFS has been known to exist.

This author
claims that the C.D.C. has long ignored and invalidated CFS, and has gone so far as to misappropriate funding marked for its research. Meanwhile, patients have fallen victim, not only to the syndrome, but to "quackish theories and harsh ideologies." This has made the everyday pain and the nearly impossible recovery even harder to bear.

Clearly, many more people are at risk of contracting chronic fatigue syndrome. And thinking of all the potential that could stifle -- writing more books, having and participating in families, proposing legislation, finding more cures -- seems to make us all sufferers of this neglected syndrome.

Here's hoping that this study marks a new chapter in understanding and halting chronic fatigue syndrome.

What do you know about chronic fatigue syndrome? Are you a sufferer or do you know someone who is? Have you ever believed it was a made-up, unfounded affliction?


[photo credit: Getty Images]

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From the Community…

Comments 1-10 of 56
  • mighty_mouse's Avatar
    Posted by mighty_mouse Wed Oct 21, 2009 7:54pm PDT

    yea, wow. that is really sad....

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  • Trish's Avatar
    Posted by Trish Thu Oct 22, 2009 6:28am PDT

    most people dont realize that it is a very real, very frustrating condition. i have Fibromyalgia and the CFS that goes along with it. so i spend most of my days exhausted and in pain. its frustarating trying to do normal activities, because even though i look like a normal 21 year old on the outside, my body can only handle about half as much as people twice my age.

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  • Ahleah G's Avatar
    Posted by Ahleah G Thu Oct 22, 2009 11:31am PDT

    I've read the study and think it's encouraging. But it is preliminary work showing that most people with chronic fatigue have the virus, not that having the virus later causes them to develop CFS. Unfortunately science can only go so fast, in large part because the money needs to be there to do the research. Eventually we will be able to get to the bottom of this.

    My mother has fibromyalgia and I saw firsthand how she was treated - people just think you are being whiny. It's the same thing with chronic fatigue - oh, you are just tired all the time. But people don't realize just how much it affects you and that it is more than just being tired.

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  • martza's Avatar
    Posted by martza Thu Oct 22, 2009 3:30pm PDT

    oh wow i dint know this at all!

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  • Magical Flyer's Avatar
    Posted by Magical Flyer Thu Oct 22, 2009 10:08pm PDT

    This gives me a little hope, I have had CFS and Fibromyalgia since I was pretty young and people just don't understand since these conditions have been so completely discredited and downplayed. It is really frustrating to have to deal with CFS and Fibromyalgia in the first place let alone be without any real help out there or support. I hope that more research will be done that will actually HELP CFS sufferers.

    Hang in there Trish I know how you feel and I am your same age. Take care.

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  • G's Avatar
    Posted by G Thu Oct 22, 2009 11:17pm PDT

    I have had it for about 18 years. It started when I was under an extreme amount of stress due to a horrible divorse and a unduely stressful job. It's as if your body just gives out. You have absolutly zero energy, you ache and you just lay in bed. I tried to seek medical help at that time. It was'nt very helpful as doctors were just starting to speak about it but most did'nt believe it existed. I went the natural route. A health clinic whom believed me but, I believe saw $ signs when they treated me. There where the hard to get drugs out there that were supposed to kill off the fungus in your system. That's what the theory was at the time. Anyway I stayed in bed for 6 months straight. I finally went to a really good health food store and bought a high powered vitamin powder that I would mix up each day and drink. I don't remenber the name of the product but all I do know is that slowly I returned to the living. The thing is it never really leaves you. I still get sick constantly . Each season I go through hell. I can catch the flu and get it back a week later. I now try to take vitamins, fish oil each and cut down on sugar. Sugar seem to make it worse. When I eat better I do a bit better. My best advice is to rest, stay away from junk ,take vitamins and try not to let stress get to you.

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  • classicalmuzclovr's Avatar
    Posted by classicalmuzclovr Fri Oct 23, 2009 11:12am PDT

    I have it too.... fibromyalgia, at least that's what my docs say...

    I think the fact that there is no conclusive blood test, and many times all blood work is normal, and there are no outward symptoms, only pain, fatigue, malaise etc... it's hard for people who don't have this, to really believe and understand how real it is...

    I am in pain just about every day. I'm so tired I cannot function sometimes...

    But I do have good days, where I feel pretty great.

    The best way to describe the overall feeling of fibromyalgia, is how you feel when you're coming down with the flu.

    Body aches, stiffness, soreness, exhaustion...

    Not to mention chest pain, IBS, headaches, memory loss (known as fibro fog)

    And one of the major issues, severe sleep troubles/ disorders...

    I hope to God they find a way to cure this, because I'm sick of feeling like dirt all the time....

    The fact that this is like an epidemic now, among women that are child bearing age... gives me pause.

    I think it's strongly linked to stress, traumatic life events, and they are doing much research, and believe that the primary cause of fibromyalgia, might actually be sleep disorders....

    Here's to all you ladies who suffer with this! May you be well soon...

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  • JDPsmiley's Avatar
    Posted by JDPsmiley Fri Oct 23, 2009 1:58pm PDT

    Nah Nahnny boo booo told ya it really exists, but does anyone (I personally know )listen? Well sometimes, but not lately!

    Well this study proves me right ;)

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  • JDPsmiley's Avatar
    Posted by JDPsmiley Fri Oct 23, 2009 2:01pm PDT

    My mom has suffered from fibro for years, and claims she was exposed to a virus while pregnant w/ me. The Herpes #6 is what gave her her fibro symptoms.

    Could that be a possible cause for me to get CFS?

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  • ShebyShe's Avatar
    Posted by ShebyShe Fri Oct 23, 2009 2:41pm PDT

    I was diagnosed with Fibromyalgia and Chronic Fatigue Syndrome over 20 years ago. I didn't know what it was and no one else did either. My doctor at the time must have stayed up to date with what was going on in the "medical" arena. It was a few years before I actually met another person that had it. Of course now, everyone you know either has it or has family or someone they know that has it.

    It just doesn't take back all the guilt from having no energy to do things that other people expected me to do. My husband has never understood it and I believe to this day, he still thinks that I am just lazy. Whatever, there was nothing that I could do about it. I am now in my early 50's and it has only gotten worse over the years.

    I have a script for Nuvigil to stay awake during the day, but I can sleep while taking that. I have been tested for everything possible from head to toe, but no one can explain my headaches. It just makes me cry right now while I am laying on my bed with my laptop, in so much pain and 25 years has gone by and so little has been done to find a cure. A doctor told me many years ago that if it was more men that had this instead of women, that they would have found a cure by now. Sad!

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