Healthy Living

Tuesday, October 7, 2008

Should you hold off on hormone replacement therapy?

At a global menopause summit in Madrid recently, experts from the International Menopause Society announced that hormone replacement therapy (HRT) may be safe after all. Once widely used not only to treat menopause symptoms, but also to lower chronic disease risk, HRT fell from grace when the results of the Women's Health Initiative (WHI) were published in 2002, suggesting that HRT confers modest, but measureable, net harm rather than benefit.

The view announced this week is that the WHI studied only older women, past age 60. The menopause experts suggest that HRT appears to be safer for women in their 50's, based on their review of the scientific literature.

There is another consideration, not raised by the menopause society. The WHI studied only one variety of hormone replacement, called Prem/Pro. "Prem" stands for Premarin, estrogen made from the urine of pregnant mares (female horses). Human estrogen was not studied. "Pro" stands for medroxyprogesterone acetate, a synthetic progesterone roughly 20 times as potent as human progesterone.

Colleagues of mine with expertise in this area have long felt that study of Prem/Pro was not a sound basis for generalization to all potential varieties of HRT.

Where does this leave us? With some uncertainty about where baby ends and bathwater begins, and with bickering likely for some time to come. I think some varieties of HRT may yet prove to offer more benefit than risk. More study and scrutiny are clearly warranted. In the interim, you and your doctor will have to look carefully at pros and cons, and make a personal choice.


More Ways to Stay Healthy
Look Up Your Rx in Prevention's Drug Encyclopedia

Get Expert Advice on Women's Health Issues
Spice Up Your Sex With These 10 Hot Tips
Syndication:

From the Community…

Comments 1-10 of 13
  • keeperofusedshadows's Avatar
    Posted by keeperofusedshadows Fri Jun 13, 2008 2:48pm PDT

    I'm going through menopause at the age of 32 which is not suprising since I have a double uterus, an incomplete septum, only one fallopian tube and ovary which is bent back and attached to the double uterus, and cysts and polyps I've dealt with most of my life. Add to that the fact that I started my period at age eight, and it's no wonder I'm having early menopause. Despite all my problems I have two children and have had two miscarraiges. It's suprising to me that I haven't been put on any HRT, and I bet a lack of information on how they affect a woman might have something to do with it.

    Report Abuse
  • Pollyanna Passion's Avatar
    Posted by Pollyanna Passion Fri Jun 13, 2008 3:37pm PDT

    I believe that HRT is highly unnecessary in most cases.There are a number of herbal or non-drug preparations on the market that are known and have been proven to help alleviate the symptoms of menopause.Eg evening primrose oil.All drugs have unwanted side effects so no one can convince me that dosing myself with hormones after age 45 or 50 as the case might be, can be harmless.This is just another case of these already super wealthy drug companies trying to make more money.

    Report Abuse
  • Aurora's Avatar
    Posted by Aurora Fri Jun 13, 2008 4:44pm PDT

    when women reached menopause, they use to give women high doses of estrogen since thats what they were lacking. this was before they realized that you actually dont need as high of a dosage as they thought and before they knew of all of the bad side effects that it caused. they definitely know a lot more now than they use to and have done tons of research, but going on any type of hormone treatment can be harmful.

    Report Abuse
  • Amy W's Avatar
    Posted by Amy W Sat Jun 14, 2008 5:01am PDT

    There are other solutions. Besides menapause is the beginning of another stage in a woman's health and body. Why do we not want it to happen? I have a sneaking suspicion that if we didn't have so many Chemicals in our bodies in the first place, from the foods we eat and the air we breath and the plastic everything...we might go through menapause with flying colors. So my bottom line on things like this are, do your own research, feel comfortable with YOUR decision and find someone ( M.D. Naturopath, Chiropractor, etc , or a TEAM fo doctors) to help you with the end goal. In the end YOU have to feel comfortable about what it is you are doing with your own body.

    ~Amy~

    MSLC

    http://groups.yahoo.com/group/theautoimmuneepidemic

    http://groups.yahoo.com/group/totalhealth2008

    Report Abuse
  • tgonzales59's Avatar
    Posted by tgonzales59 Sat Jun 14, 2008 8:29am PDT

    I'm 49 and going through menopause. no harmone replacement due ovarian cancer in my faimly. My M.D. gave me a RX for depression and it helps.I still have mood swings, at times hot flashes! I'll just be glad when it is all over.

    Report Abuse
  • seep3's Avatar
    Posted by seep3 Sat Jun 14, 2008 3:18pm PDT

    I am 50 years old. I have tried every natural product on the market from pill form to cream. Finally i tried acupuncture. Treatment with herbs did seem to help, but it cost me almost $400 a month. With our economy the way it is, this was more than a normal person could afford. Unfortunately, insurance does not cover anything of this nature. So now I am back to hot-hot flashes ( unbearable) mood swings, depression, ect. Now who has an answer for this.

    Report Abuse
  • titsound's Avatar
    Posted by titsound Sat Jun 14, 2008 7:41pm PDT

    BIOIDENTICAL ESTROGEN OF NATURAL HORMON CALL DOC.MAGIDENKO IN PHILADELPHIA":TEL---215-3229797,HE IS #1 TO HELP WOMEN

    Report Abuse
  • Isky's Avatar
    Posted by Isky Sun Jun 15, 2008 1:22am PDT

    I had a complete hysterectomy when I was 28, because of ovarian cysts. I started taking Premarin at 2.5mg/day (If I remember correctly). Gradually, the dosage has dropped to .625mg/day now. I'll be 70 next week. During those years doctors have frightened, and then reassured, me about using conjugated estrogens. Cervical cancer scare - have a pap smear regularly, Then, sorry, you cannot get cervical cancer because you have no cervix! Breast cancer scare - no previous family history of it and luckily I don't have it. Heart disease scare - all tests show it's fine! I believe that Estrogen kept me young, moist in the right places, and with no bone loss. I look 50, thank you. Now what do I do about hair loss and near-sightedness!!!!

    Report Abuse
  • linnameng78's Avatar
    Posted by linnameng78 Sun Jun 15, 2008 4:53am PDT

    What a ^%$&$%$ woman!!!!!!!!!!!!!!!The magazine SEEKING GOSSIP reported her joined the beautiful women for wealthy men personals site "S e e k i n g R i c h . c o m " and she is mentioned to find her sugar boy there! the magazine foolx she????????????or fools us。。。。

    Report Abuse
  • 50+ going on 30+'s Avatar
    Posted by 50+ going on 30+ Sun Jun 15, 2008 5:52am PDT

    I can totally relate to the 70/50 year old menopausal Woman who took Estrogen in spite of all the precautionary WARNINGS. For me there was no option. Take the "pill" or incinerate. I've been taking a 1.25mg dosage daily, and have been for 10 years running, although I drilled down my mg dosage for one year per my docs recommendation for breast cancer prevention. I too feel that it helped stop or strongly reduces the over heated moisture radiating from my upper body at its own beckoning; amongst other symptoms. The emotional roller coaster and weight control are a couple. And, I have an active sex life with my partner for over 6 years and never once experienced dryness or lack of libido. I guess I just took a leap of faith that the acceptance of aging requires a little help now and then. It also helped me to increase my exercise activity and really focus on eating healthier foods. Oh, and laughing out loud now and then even if you laughing at yourself doesn't hurt either.

    Report Abuse
Comments 1-10 of 13

leave your comment

You must sign in to post a comment

Sign In for personalized information

New User? Sign Up

Updates Chatter on Shine...

Health Byte

Does the election have you all worked up? Take a break from the hype and instead, take some deep breaths.