Swine Flu - Complication and Hospitalization Risks

Obese individuals (BMI 30 or higher) are in a state of mild "cytokine storm" making them vulnerable to influenza complications and death. A CDC report dated July 17, 2009 noted that of ten intensive care patients hospitalized (University of Michigan Health Center) for H1N1 influenza, nine were obese including seven who were severely obese (BMI 40 or higher). Three of these patients died due to complications. The report noted that "Clinicians should be aware of the potential for severe complications of novel influenza A (H1N1) virus infection, particularly in extremely obese patients." Also, a study conducted by Beck out of the University of North Carolina Chapel Hill noted that obese mice had a 40% mortality when exposed to H1N1 influenza as opposed to 4% mortality in non-obese mice.

A recent analysis by Anne Schuchat, MD, of the CDC - National Center for Immunization and Respiratory Diseases - shows that individuals with certain underlying chronic health conditions are also at increased risk of complications and hospitalization.

Among 500 hospitalized children suffering from swine flu complications, the most common underlying conditions included asthma, chronic lung disease, neurologic and neuromuscular disorders, and sickle-cell anemia and other blood disorders.Of the 1400 adults hospitalized, Dr. Schuchat noted that asthma, diabetes, chronic lung disease, chronic heart disease, and immunosuppression were the most common exacerbating conditions.

Dr. Schuchat also noted that 6.1% of hospitalized adults were pregnant. She cited the main reason for this finding to be the mother's natural immune system suppression as protection against her body reacting negatively to the fetus. Also, during pregnancy many women suffer from airway compression and this could decrease the mother's ability to fight off the infection as well.

Underlying medical conditions and pregnancy, as well as central obesity, are risk factors which increase hospitalization and mortality associated with swine flu infection. Individuals at risk should speak to their doctor regarding these risks, and the pros and cons of immunization. Also, those considering vaccination should request preservative (Thimerosol) free vaccines, especially pregnant women and infants under 6-months of age.

Dr. Sardone
Author of The Naked Truth: Overweight, Overwhelmed and Confused
www.drsardone.com