There's an excellent and completely detailed story up on WebMD right now about the best ways to take care of your skin in your 20s, 30s, 40s, 50s, and beyond. It outlines, step-by-step, a "no fail" plan for each age group-including the ingredients you should be looking for in a cleanser, moisturizer, and nighttime treatment. Some of it is kind of complicated and, honestly, I started to glaze over when it got into things like prescriptions creams. But it's still a more informed strategy than my current Soap-Oil-Of-Olay-Pray technique and really any scientific defense against my ever-deepening mouth puppet lines is worth a try.
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