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    Do you need this sex pill?

    In her leopard-print shirt and plumped-up ottoman pout, soap star Lisa Rinna tells CBS news, "I lost my sex drive." It seems we now have our own female Bob Dole.

    If you've never heard of hypoactive sexual desire disorder (HSDD), check out a site called Sex Brain Body, where Rinna is featured. You'll learn that while the cause of low libido is unknown, the brain's neurotransmitters are thought to play a role. You have to read the fine print to make out the astroturfing ("with the support of sponsorship from Boehringer Ingelheim Pharmaceuticals.") What's interesting is how this sex- brain-body campaign (also check out the Discovery Channel's series on female sexual dysfunction) is being rolled out before the star is born. That would be the HSDD drug Boehringer Ingelhiem has developed for young women-it works on the brain-which will go before the FDA on June 18th for approval.

    I wouldn't have known anything about it, had I not gone to a screening of Orgasm Inc., a documentary about another drug company trying to come up with the next female Viagra. Several people from Boehringer Ingelheim were there to check out the climate. Let's just say, it was testy.

    "I think the Boehringer Ingelheim campaign is unethical," says Karen Hicks, PhD, a spokesperson for The New View Campaign, which is trying to block the drug's approval. "Even though they don't mention the drug on the site, and the quality of the information they have about HSDD-if you believe in it-is quite good, this is totally premature."

    Should this sex drug pass? I don't have the answer, but I know we should be asking the questions:



    So what is this drug? Flibanserin-or Girosa, the likely brand name-was originally tested as an antidepressant (it didn't work) and targets serotonin receptors. When I asked Boehringer Ingelheim how it affects libido, they responded via email through Ogilvy PR, "It is hypothesized that neurotransmitters within the brain are affected in women suffering from HSDD. While the specific mechanism of action is still being studied, flibanserin is believed to act on these neurotransmitters." That's a lot of hypothetical for a drug you have to take every single day.

    Does it work? According to the company's studies (read a report here), premenopausal women with HSDD who took flibanserin, reported increased desire and sexual function. Further-and the part the FDA will likely focus on-the 450 subjects who took the drug, had more "sexually satisfying events" during the 24-week study period than the 521 women on a placebo. The difference was an increase of 2.1 verses 0.9-in other words, a little over 1 more "sexually satisfying event" during the 6 months. "I don't think that's enough of an improvement to fix the disparity between a woman's libido and her man's," says Susan Bennett, MD, assistant professor of medicine at Harvard Medical School, where she teaches a class on women's sexuality. "Targeting the central nervous system for the treatment of sexual dysfunction is a really good idea. But even if this drug is safe, I don't think it will be a big seller."

    Is HDDS even a disease? Many experts, including Bennett, are dubious. What is "normal" desire for women? Wanting to get it on every day? Once a week. Twice a year? "For the vast majority," Bennett says, "low desire is just a normal part of their existence. The reasons are myriad-work, kids, lousy relationships, and a natural tendency not to have the libidinous drive men do."

    Liz Canner, who made Orgasm Inc., believes the whole thing has been pushed on us by the drug industry. (The film is great-I highly recommend watching it-alone or with the girls.) Canner's almost decade-long journey started when she was hired by Vivus, a biopharmaceutical company, to make erotic videos so they could test an orgasm cream they were developing for women with "female sexual dysfunction" (which includes HSDD.) They let her film while she was there. At one point in the movie, she asks the company's founder, Virgil Place, MD:

    "Is there anything organically wrong with these women you can locate that [the cream] will address?" From behind his desk, he thinks a minute, then looks into the camera: "I can't answer that question."

    Darby Stephens, the manager of clinical research, awkwardly explains the company's interest in female sexual dysfunction this way: "We had concepts in development, but somehow it got picked up that we had drugs. The market went wild. We didn't even know what the disease was."

    (When I contacted Vivus's CFO, Timothy Morris, he responded, that the footage of the company was "filmed nine years ago and is out of date. Over the past few years,the compay has discontinued the development of products for female sexual health." Vivus's current focus, he says, is new obesity drugs.)


    "I didn't go in trying to frame anyone," Canner tells me recently. "I liked the people I worked with. It wasn't until later when I looked at the footage that I started realizing they were in the business of developing a disease in order to sell the drug-and putting women's health at risk for their own profits."

    Is it safe? So far, Boehringer Ingelheim, hasn't found reason to suspect otherwise. The side effects, which include daytime sleepiness, insomnia, nausea, and anxiety, appear mild to moderate, and fade in a couple of weeks. But a six-month trial is not very long, and we only have company studies to go by. New View is extremely concerned. "There isn't enough safety information and we just don't know enough about the effect of serotonin on the brain," says Hicks. "Without having good evidence of all the effects that flibanserin will have, it's a complete crap shoot."

    Do we need a sex pill? I certainly hope that any woman who is distressed about her sex life gets help. But even if this drug turns out to be safe and effective, I'm concerned about the idea of libido pills playing into a culture that is already hyper-sexualized, raising our expectations about how much we should want sex and get off on it. To our endless list of things we fail to live up to-beautiful, thin, smart, busty, cellulite-free-now we're going to add "always hot to trot"? Bennett would rather see an Rx for knowledge. "I'm not anti-pharma, and I believe in better living through chemistry," she says. "But I think there's a tremendous misunderstanding in society about women's sexuality. Just because you don't have an orgasm, doesn't mean you aren't enjoying sex. Men and women are very different. And their libidos are very different. And I don't think all of that can be fixed even if they develop the perfect drug."

    What do you think? Should flibanserin be approved June 18th?

    If not, you can find out about taking action at the New View Campaign.
    For more about sex drive...

    How active is yours?
    Ways to increase it
    Female Viagra: Bad News?





    [Photo Credit: Getty Images/MedicalRF.com]

























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    49 comments

    • Aeris  •  1 year 11 months ago
      I for one would LOVE a libido-boosting pill (as long as it's effective and safe). Me, and many other girls I know, have trouble sustaining high libidos during long-term relationships and marriages. And we're all young! My bf does so many wonderful loving things for me, helps me with housework, errands, cooking, etc. He does all the things women claim they want from a partner in order to feel "in the mood", plus he's extremely attractive, smart, and funny. And yet I still have trouble with desire. This problem has haunted me my entire life and no gyno has been able to tell me anything other than "get more exercise and take time out for each other". Ummm, I work out 3-5 times a week, eat very healthy, and we DO take time out for each other. I want my magic pill since nothing else is working! :P
    • AdamantiumMagnolia  •  1 year 11 months ago
      vikb... what about those women who are fortunate enough that they are neither overwhelmed by the job or depressed and they also have the type of man you describe and still have extremely low libido compared to just a few years ago?
    • SILENT KNIGHT  •  1 year 11 months ago
      It should be approved like every other drug sold for a profit that experiments with female complexities regardless of the supply and demand illusion. Whoever these scientists are that come up with these inhuman and un-natural aids to human existance...they are the smartest dumbest most ignorant fools with the audacity to play GOD. Men just need to respect, love and treat thier women better, so they wont be afraid, feel ashamed, over compensate or compete to feel beautiful, needed, sexy and properly balanced. A pill will never do what a simple kind word, a deeply emotional and affectionate touch and a closer attention to details can do for the over all completeness of the soul aswell as enlightening the most sensitive human frailties of intimacy. It's easy to raise a pulse and infuse someones spirit with a healthy positive energy that causes everything to be and connect beyond what can be explained. Some people just need to learn how to admire and appreciate rare beauty as a majestic art rather than break it into pieces and charge people to see it put back together as they saw fit.
    • Jeffrey  •  1 year 11 months ago
      Keep in mind this isn't "female Viagra." Contrary to popular belief, Viagra does NOT affect a man's sex drive. It doesn't make him want sex or want it more. It merely allows him to have an erection when stimulated. If this new thing just affected blood flow (which doesn't seem to be what the article is describing) then it's be "female Viagra" but apparently it affects the actual libido.
    • Michelle  •  1 year 11 months ago
      I took part in the original drugs studies for Flianserin and I can tell you that it absolutely 100% works and I can only hope that it is approved by the FDA, it has the potential to change a lot of women's lives.
    • sun2go  •  1 year 11 months ago
      This goes for women as well as men---should you really be having sex if you don't have the drive or ability to do so? Animals don't, and this typically enables them to only reproduce under ideal genetic and environmental circumstances, thereby preventing weaker genetic traits from being reproduced. If only humans were so ethically evolved, rather than scientifically evolved.

      Should you really be taking a pill to compensate for and mask the true physical and/or emotional reasons for your symptoms?

      Should such people be procreating from the artificial sex drive and performance from such drugs, if they don't possess the natural desire and ability?

      What does it mean genetically for future generations of children born to parents under the influence of sex drugs?

      If you can't do it and/or don't want to, nature's telling you that you shouldn't be having sex and/or you shouldn't be reproducing. Get yourself straightened out physically and mentally instead of taking a sex drug. You'll get to the root of your problem, and you'll be healed more thoroughly from your issue.
    • MichelleG  •  1 year 11 months ago
      vikb: precisely!!! its not about low sex drive, its about a lack of love & affection, THAT is what turns women on, not just a physical or chemical reaction in the brain.
    • CAZANOVA 2010  •  1 year 11 months ago
      hi 2 all i wish you fine in a sexlife
    • Mysterious Gryphon  •  1 year 11 months ago
      I think that the point that many of the posters here are trying to make is that every woman is different. Some women go through life with the libido of a 17-year-old; others never had much to begin with; and still others find their interest in sex drop for a variety of reasons. This is DEFINITELY NOT a made up concern.

      For me, when I went on hormonal contraceptives, my whole being changed. I went from horny ALL THE TIME to "meh". (And I'm married to the man of my dreams, who couldn't be more helpful at home - it's not a housework problem.) I'm off the hormones, and I take an herbal supplement that helps, but I ask my gynecologist every six months about what more I can do to get back to being myself.

      In my opinion, ANY and ALL research into women's sexuality is LONG OVERDUE and WELCOME.
    • boo yow  •  1 year 11 months ago
      lisa rinna is a horrible example. look at her obsession with her lips. they have always been way out of proportion with her face--i think she's been pumping them up since 1988 on dayzz of our livezz...anywho, she's also unnaturally super skinny and has fake boobs......it seems that women that are obsessed with having some hybrid perfect body are in fact not really sexual beings to me. i am average sized and no fake parts.....there are many women that would have been a better example, but weirdly using lisa as a reference, it proves AGAIN that it's confidence and self-esteem that makes a person feel sexy and allows others to respond to the sexuality that a women gives off....full circle all the way!!!!!
    • dennis  •  1 year 11 months ago
      love is what makes the world go around no need for any pills
    • Irene  •  1 year 11 months ago
      Don't need a sex pill...just need a good lover.
    • runt  •  1 year 11 months ago
      smoke pot it works great
    • Peachy1  •  1 year 11 months ago
      I don't know about this one ...... It seems like they are giving it the bum's rush thru testing/clinical trials. I'd rather have an option that's been thoroughly tested, that they have SOME CLUE what the side effects are then have that section of the medication information be just a giant question mark. What about long-term side effects? Good Lord, if you go thru the change in your mid 40's, you have the prospect of 30 - 40 more years to be around, taking a pill to be able to have sex or dealing on your own. So what's the marketing slogan gonna be? "You're gonna die anyway - Why not die with a smile on your face?
      Sorry if this didn't quite make sense --- My coffee hasn't kicked in yet ........
    • Peachy1  •  1 year 11 months ago
      D M, your comment was rude and in very poor taste. So, you're advocating comatose sex? How is that helping?
    • Mom194387  •  1 year 11 months ago
      While I totally support each person's right to decide what is best for their body and lifestyle given whatever options are available to them in the marketplace, I have to believe that much of what society coins, "Women's Sexualty" is really just "Men's Sexualty" re-packaged.

      On average, men and women are different when it comes to sex, desire, affection, libido, and orgasm... and that's okay. However, when society, especially pharmaceutical companies and the MEN in relationships with WOMEN, begin asserting that women's sex drives and sexuality is FAULTY because it's no identical to men's... that's when this all becomes a problem.

      If sexualty was defined from the female perspective, pharma would be pushing pills that lower libido in men and increase their cuddling response!
    • A Yahoo! User  •  1 year 11 months ago
      Saying low libido in women isn't a problem is unrealistic. First let me address menopause. Before I hit menopause, I wanted sex for a few hours a day, everyday, & my sex drive matched up perfectly with my man. After menopause, my sex drive went to zero. I literally never wanted to have sex, period. I also felt emotional disconnect from everyone--my kids, my friends, & my man. With bio-identical hormone replacement ( tailored to the individual ) I am now emotionally reconnected, but my sex drive is still very low, but at least it exists. And yes, when you go from wanting to make love to your partner everyday to never, ever wanting to, it is a problem, & I am happy to try whatever aids may be out there.

      Additionally, in most of my relationships, my sex drive has been much higher than my partner's. Let me tell you, after a while, you don't feel like they just don't want to have sex with you, you feel like they are rejecting you as a person. It is very damaging to your self-esteem to feel so unwanted by the person you love. This is what most men feel in their relationships, when their sex drive is so out of sync with their partners. So for that reason, yes, women's sex drive being so much lower than men's IS a problem. And for women who claim to love their boyfriends/husbands, they should be willing to look into what they can do to make their men feel more loved, which does include more sex.
    • SILENT KNIGHT  •  1 year 11 months ago
      Women and everything about them will always be a mystery to all those who don't seek to understand. A sex drive is something natural that doesn't need a switch that you can swallow to turn it on or off. The best things in life are simple, free and take time...and when it's worth it, it may even take a life time. Besides that a sex drive is a force of nature beyond chemicals in the body. The mind, the heart and everything else it takes for sex organs to work is a delicate balance. Why complicate something as simple as LOVE and suffer the effects of inbalance? If you think things are bad now, wait til they come up with another bright idea they can't quickly change back once they get the ball rolling.
    • Dubs  •  1 year 11 months ago
      I wish Big Pharm would come out with a pill that would affect the neurotransmitters revolved around people complaining about how their own personal autonomy is going to be affected by some company coming out with a pill for those that would "like to try it".

      Or maybe a shot that would decrease the whining hormone for those that internalize and read into things too much. If its too orwellian let me know.

      God forbid if it were the men with the low libidos everyone would be over-analyzing why he isn't attracted to his spouse / SO/ GF anymore as well as the other myriad of tangential complaints this argument derives. It goes both ways people..double binds suck. Get over yourselves.
    • Dashing Darné  •  1 year 11 months ago
      I think most women would prefer to have an orgasm than not.
      If a pill were developed and proved to be safe for women I'm sue it would be bigger than Viagra!

      Eventually all women will go through menopause and large percentage of them report a dramatic reduction in desire or NO desire, as well as dryness and pain during intercourse.
      Some men have used this as an excuse to "trade in for a younger model"

      It's also natural to want to take advantage of new options that come through new medicines. Hopefully we won't learn 5 years from now that this pill causes cancer or some other deadly disease!

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